Overview
VAMPIRE (Variant Annotation Method Pointing to Interesting Regulatory Effects) provides a tool for the user to explore annotations encompassing 1D epigenomic signatures, variant impact on protein and gene expression, chromatin conformation information from Hi-C and similar technologies, as well as publicly available GWAS and PheWAS results, creating a comprehensive annotation profile for variants from recent trans-ethnic blood cell trait publications and preprints with a flexible interface for adding additional future GWAS results.
To visualize and leverage these multiple annotation categories for further analysis or prioritization of experimental validations, VAMPIRE effectively and efficiently displays and integrates relevant variant information, allowing the user to investigate either all the variants annotated or subsets based on annotation category groupings ('Search by Annotation Category Group' tab), searching either by variant ('Search by Variant ID' tab) or by gene name. ('Search by Gene Name' tab)
Last Updated: December 10,2020